ea0029p1409 | Pituitary Clinical | ICEECE2012
Ratnasingam J
, Karim N
, Paramasivam S
, Tan Tong Boon A
, Vethakkan S
, Choong K
, Pendek R
, Chan S
Background: Radiotherapy is the mainstay of NPC (nasopharyngeal carcinoma) treatment and recently there is increased use of concurrent chemo-irradiation (CCRT) to improve survival. The irradiation field for NPC includes the base of skull, risking radiation damage to the hypothalamic–pituitary (HP) axis.Aims: To evaluate the prevalence of HP dysfunction in NPC survivors post-irradiation and to compare the risk of developing HP dysfunction amongst pat...